Frontline Plus Flea & Tick Treatment for Large Dogs (Up to 88 lb) – 3 Treatments

Protecting Your Large Dog, One Month at a Time

Frontline Plus for Dogs is a fast-acting, long-lasting topical solution designed for large breeds, delivering month-long protection against common parasites. This waterproof formula targets fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease. By combining fipronil with (S)-methoprene, the treatment helps interrupt the flea life cycle and guards against new infestations when used as part of a routine plan. With more than two decades of trust behind the brand, Frontline Plus is a familiar choice for many households seeking a simple, reliable protection approach.

The application is a single dose placed at a spot on your pet’s neck. From there, the treatment distributes through the skin’s oil glands, creating a reservoir that slowly replenishes the active ingredients. This means protection can endure through normal daily activities, and the product remains potent even if your dog gets wet. Each package in this large-dog pack provides three monthly doses, offering a straightforward way to maintain year-round coverage without frequent reordering.

Frontline Plus for Dogs is suitable for puppies as young as eight weeks and 5 pounds, making it possible to start protective care early in a dog’s life. The line also includes a cat-and-kitten formula, so households with both dogs and cats can maintain a consistent protection routine across pets. To support ongoing protection, many owners choose monthly reminders or subscribe-and-save options to minimize gaps in coverage and reduce the chance of running out of product.

Key considerations for use include applying the treatment once per month, following label directions, and treating all pets in the household to reduce the potential spread of fleas and ticks. While results can vary based on environment and exposure, Frontline Plus provides a practical, easy-to-use option for many pet families seeking a dependable, non-intrusive care routine.

Included in this pack: three topical treatments designed for monthly use, suitable for large dogs up to 88 pounds. This trio supports steady, predictable protection across a typical overlap of flea and tick seasons. For households with multiple pets, explore the broader Frontline product family to match each pet’s size and needs. Stay connected with the brand for updates, tips, and new product releases that support ongoing pet care.

• Fast-acting topical formula that spreads across the coat
• Waterproof protection that can endure normal activities and rain
• Kills fleas, eggs, larvae, chewing lice, and ticks
• One monthly dose for up to 30 days of protection
• Suitable for puppies eight weeks and older, 5 pounds or more
• Pack includes 3 treatments for easier year-round coverage

• Easy at-home application with minimal disruption to daily routines
• Part of a broader Frontline range, with a cat/kittens formula also available
• Optional subscription and savings to keep protection steady
• Consult the label directions for use on pregnant or nursing pets