FRONTLINE Plus for Large Dogs (8–88 lb) Flea & Tick Treatment — 8 Treatments

Overview

FRONTLINE Plus for Large Dogs delivers fast-acting, long-lasting flea and tick protection for pets 8 weeks or older. This waterproof topical targets adult fleas, ticks, chewing lice, mites, and flea eggs and larvae, helping break the flea life cycle and guard against new infestations. The formula is designed to deposit in the sebaceous glands, creating a reservoir that replenishes protection as your dog goes about daily life, even after getting wet.

Key benefits at a glance

• Fast-acting protection against fleas, ticks, chewing lice, mites, and flea eggs and larvae
• Waterproof 24 hours after application, so baths or swims won’t interrupt protection
• One monthly dose provides ongoing protection for a full 30 days

How it works

The treatment is applied to a single point on your dog's skin and distributes across the coat, depositing in the sebaceous glands. This reservoir helps replenish protection as your dog goes about daily activities, even after getting wet. Applied once a month, it forms a continuous shield around your pet.

Usage tips for best results

• Apply every month for continuous fleas and tick protection
• Suitable for puppies 8 weeks and older, weighing 5 pounds or more
• Ideal for households with multiple pets; follow label directions for each animal

Trusted by pet owners for over 20 years, FRONTLINE Plus combines a fast start with reliable, month-to-month coverage. Subscribe and save to simplify year-round protection, and visit our Frontline brand store for tips and related products. Always read the label for dosing instructions and safety information. This product is designed to be part of a routine that helps keep your dog comfortable and ready for adventures, without making guarantees about health outcomes.

Real-life use scenarios

• Dogs that spend time outdoors on parks, trails, or yards stay protected between monthly applications
• Families with more than one pet can keep a straightforward monthly schedule to help reduce flea and tick exposure
• Dogs that swim or get regular baths can continue to receive protection 24 hours after application